- Research suggests exercising is a powerful tool for the prevention and management of depression, in part by normalizing insulin resistance
- Mechanistic studies have also linked the antidepressant effects of exercise to molecular mechanisms involving kynurenine, myokines, BDNF, the endocannabinoid system and beta endorphin
- By allowing for more tryptophan to be transported into your brain, exercise raises your serotonin and inhibits conversion into kynurenine, thereby boosting mood and preventing depression
- Low BDNF levels have been implicated as a central component of depression, as depressed patients typically have lower levels than healthy controls
- While exercise euphoria is typically attributed to the release of endorphins, vigorous exercise also dramatically increases anandamide — an endocannabinoid — in the body, which influences opioid and endorphin receptors. The higher your anandamide level, the better you feel
Read the full article by Dr Mercola.
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